Endocrine Abstracts

Primary hyperparathyroidism (PHP) is a common endocrine disorder. It is due to a single parathyroid adenoma in 80% of cases, most of the remainder due to hyperplasia of all four parathyroid glands. The only curative procedure is parathyroidectomy, but preoperative localization can be difficult. Isotope scanning with sestaMIBI is considered to be useful in localizing any parathyroid adenoma to help guided surgery. The aim of this study is demonstrated the influence of biochemic...

The simultaneous occurrence of MTC and PTC in the same thyroid can be observed as a mixed tumour folliculo-medullar (OMS 1988) or as a collision tumour separated by normal thyroid parenchyma, which has only been described in less than thirty patients. We report two cases.Case 1: A 72 years old woman who underwent total thyroidectomy for a multinodular goiter. Histology showed a 2.5 cm CPT in the left lobe and a 4.5 cm CMT in the right lobe. She received ...

Introduction: BRAF (V600E) mutation is the most frequent detected genetic change in papillary thyroid cancer (PTC) and its presence has been related to aggressive clinical and pathological features. Lymph node metastases (LNMx) are common in PTC and are associated with an increase in loco-regional recurrence. However, prophylactic lymph node dissection is not routinely performed because of high rate of surgery complications. Therefore, there is a need to find a good marker to ...